Preliminary information.

[vc_row][vc_column][vc_column_text]Preliminary information, they are studying why the disease pathway in Italy is more serious. One of the factors was that most Italian patients took ibuprofen at home. They combine the virus and ibuprofen in the laboratory and came to the conclusion that the administration of ibuprofen accelerates the multiplication of the virus and that it is related to a more serious course of the disease. They recommend avoiding ibuprofen and other NSAIDS for fever, I guess similar to the association of aspirin in chicken pox leading to Reye’s syndrome.

So IF POSSIBLE try and avoid Angiotensin converting enzyme inhibitors (ACEI) like lisinopril and Angiotensin Receptor Blockers like valsartan see Lancet article.

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(20)30116-8/fulltext “Human pathogenic coronaviruses (severe acute respiratory syndrome coronavirus [SARS-CoV] and SARS-CoV-2) bind to their target cells through angiotensin-converting enzyme 2 (ACE2), which is expressed by epithelial cells of the lung, intestine, kidney, and blood vessels.4 The expression of ACE2 is substantially increased in patients with type 1 or type 2 diabetes, who are treated with ACE inhibitors and angiotensin II type-I receptor blockers (ARBs) .4 Hypertension is also treated with ACE inhibitors and ARBs, which results in an upregulation of ACE2.5 ACE2 can also be increased by thiazolidinediones and ibuprofen. suggest that ACE2 expression is increased in diabetes and treatment with ACE inhibitors and ARBs increases ACE2 expression. Consequently, the increased expression of ACE2 would facilitate infection with COVID-19. We therefore hypothesise that diabetes and hypertension treatment with ACE2-stimulating drugs increases the risk of developing severe and fatal COVID-19. “[/vc_column_text][/vc_column][/vc_row]